Published September 25, 2022 | Version v1
Journal article Open

A Rare Case Of Hashimoto's Encephalopathy Responding To Plasma Exchange

  • 1. Consultant Physician, Government Hospital Palsana
  • 2. Associate Professor, BJ Medical and Civil Hospital, Ahmedabad.
  • 3. Medical Officer, Medical College Bhavnagar
  • 4. Dow International Medical College
  • 5. Lahore Medical and Dental College
  • 6. Intern, BJ Medical and Civil Hospital, Ahmedabad.



Hashimoto’s encephalopathy is one of the rare causes of encephalopathy of unknown etiology. It manifests with neuropsychiatric symptoms. The estimated prevalence is 2/100,0001. Hashimoto’s encephalopathy is characterized by elevated antithyroid antibodies in absence of infections, tumors or stroke of central nervous system2-4. The disease manifests with wide array of clinical features which can be cognitive fluctuations, ataxia, myoclonus, seizures5-10. Psychitric manifestations like depression, mania, psychosis, and hallucinations have also been reported11-13.  Anti thyroid antibodies are considered to be the biomarkers of the disorder but the titers of the antibodies do not correlate with the severity of the disease presentation 14-15.

Keywords: Hashimoto’s encephalopathy, Hashimoto’s encephalopathy



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