The effect of Cadmium on antioxidant enzymes in the liver of fresh water fish Cyprius carpio (Linn).

ABSTRACT

In the present investigation, the fresh water fish C. carpio and Cadmium were used.  Bio assays were conducted to find LC50 96hr value of the metal to the fishes and it was found to be 1.5%.  Then groups of fishes were reared in various sublethal concentrations of Cadmium for 30days.  The liver from the control and Cadmium –treated fishes was dissected out for the estimation of Superoxide Dimutase (SOD), Catalase (CAT), Glutathione Peroxidase (GPx), and Gulutathione-S-Transferrase (GST).  In treated fishes, the liver antioxidant enzymes increased under metal toxicity suggesting the initiation of the production of these enzymes to suppress the action of ROS.  The liver might have severely affected by Cadmium as it is the site of multiple oxidative reactions.

Key words: Cyprinus carpio, Superoxide Dimutase (SOD), Catalase (CAT), Glutathione Peroxidase (GPx), and Gulutathione-S-Transferrase (GST).

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