Published October 11, 2022 | Version v1
Dataset Open

Prediction of designer-recombinases for DNA editing with generative deep learning

  • 1. Medical Systems Biology, Medical Faculty, Technical University Dresden, 01307 Dresden, Germany
  • 2. Fondazione Human Technopole, Milano, Italy

Description

Sequence data from "Prediction of designer-recombinases for DNA editing with generative deep learning" publication.
Tyrosine site-specific recombinase gene sequences with the corresponding target sequences from already published projects. Recombinases were produced with directed evolution and sequenced with PacBio HiFi.

The evolution of the recombinases sequences in this dataset were published in the following publications:

  • https://doi.org/10.1126/science.1141453
  • https://doi.org/10.1038/nbt.3467
  • https://doi.org/10.1093/nar/gkz1078
  • https://doi.org/10.1038/s41467-022-28080-7

Files

published_YSSR_sequence_data.zip

Files (20.9 MB)

Name Size Download all
md5:d75861dd31165c0dfac7633c4365a528
20.9 MB Preview Download