Lung Cancer Screening in Persons Who Never Smoked Has to be Evaluated—A Response to Letter to the Editor
- 1. Departement of Radiology National Korányi Institute for Pulmonology, Orszagos Korányi Pulmonológiai Intézet, Korányi F u.1., H- 1121, Budapest, Hungary
- 2. Division of Respiratory Medicine and Thoracic Oncology, Department of Internal Medicine V Thoracic Oncology CentreMunich University of Munich—Campus Innenstadt Munich, Germany, member of the German Center for Lung Research
- 3. Ontario Lung Screening Program, Prevention and Cancer Control Ontario Health (Cancer Care Ontario) Toronto, Ontario, Canada Department of Health Sciences Brock University St. Catharines, Ontario, Canada
- 4. Department of Experimental Oncology Institute for Oncology and Radiology of Serbia Belgrade, Serbia
Description
The authors make the argument that the so-called traditional risk factors for lung cancer (older age, male sex, heavy smoking status), apart from genetic and environmental factors, are no longer the only risk factors one should consider when defifining high risk and organizing early detection programs with low-dose computed tomography (LDCT). In general, a worldwide approach to perform early detection LDCTs in individuals without additional risk factors who never smoked cannot be mandated. Despite the fact that LDCT can detect early lung cancer in individuals who never smoked, the risk-to-benefifit ratio without additional risk factors is currently not favorable either on the individual or the population level.
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- 1556-0864 (ISSN)