COMPLEX COMPOUNDS OF BIGUANIDE WITH TERVALENT METALS PART XII. CIS-TRANS ISOMERISM IN COBALT BIGUANIDE COMPLEXES. DIAMMINO HYDROXO-AMMINO-, DIAQUO-, HYDROXO-AQUO-, DIACIDO- AND HYDROXO-ACIDO- COBALTIC BISBIGUANIDINIUM SALTS

A series of basic and normal trans-diammino-cobaltic bisbiguanidinium salts, namely, sulphate, chloride, bromide, iodide and nitrate has been prepared. Deammi­nation and dehydration of these, followed in certain cases by hydrolysis, have led to the production of hydroxo-ammino, hydroxo-acido, hydroxo-aquo, diacido and diaquo cobaltic bisbiguanidinium salts. Their trans configuration has been proved by the action of oxalic acid on the hydroxo-aquo cobaltic bisbiguanidinium hydroxide of the series, While this hydroxide forms only the corresponding oxalate, the hydroxide of the cis-series, previously described by Ray and Ghosh, has been found to give an oxalato-cobaltic bisbiguanidinium oxalate.