A case of primary synovial sarcoma of the posterior mediastinum with aortic wall infiltration with complete imaging pathway and histological diagnosis.
Creators
- 1. IRCCS centro Neurolesi Bonino-Pulejo
Description
CASE REPORT
Primary synovial mediastinal sarcomas are aggressive tumors with a very rare incidence. The few cases reported in the literature presented poor and incomplete imaging. In this report, we describe the case of a 72-year-old male patient hospitalized for dyspnoea and chest tightness. For these reasons, he underwent chest X-ray, contrast-enhanced CT, MRI, and PET, which revealed a large mass around the aortic walls. The patient underwent a CT-guided biopsy and the subsequent histopathological evaluation indicated features consistent with a soft tissue sarcoma and positive staining for vimentin. Infiltration of aorta walls was confirmed by an MRI study with cine-MRI sequences. The patient was treated with neoadjuvant chemotherapy, showing partial response. Unfortunately, during the following attempted surgical removal of the mediastinal mass, the patient deceased as a result of an aorta rupture. Our experience could help in diagnostic confidence and in differential diagnosis, especially with benign tumors such as neurogenic tumors.
Files
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