Potassium Periodate as a Volumetric Reagent. Determination of Organic Derivatives of Hydrazine

In presence of HCl, potassium periodate solution has been used as a volumetric reagent for the determination of nitroaminoguanidine, $\beta$-formylphenylhydrazine, $\beta$-acetylphenylhydrazine, adipic diphenylhydrazide, $\beta$-propionyl- phenylhydrazine, 2,4-dinitrophenylhydrazine, o-& p-chlorobenzylidene semicarbazones, cinnamylidene semicarbazone, hydrazine sulphate, semicarbazide hydrochloride, benzylidene semicarbazone, 4-phenylsemicarbazide hydrochloride, benzalazine, and 4-hydroxy-3-methoxybenzylidene semicarbezone. In the visual titrations chloroform has been used as an indicator. In potentiometric titrations, platinum electrode has been used as an oxidation-reduction electrode, coupled with a saturated calomel electrode. At equivalence point there is a sharp jump in potential in each titration.

In these compounds each hydrazino group is quantitatively oxidised to nitrogen with potassium periodate by a four-electron change.