Published October 31, 1968
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Studies in the cyclo-octane series: Part VI. Condensation of Cydo-octane-I-one-2-acetic Acid with Primary Aromatic Amines and the Formation of Substituted Pyrrol-2-ones
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Ethyl 2-carbethoxy cyclooctan-1-one-2-acetate, prepared by condensing ethyl cyclooctan-1-one-2- oarboxylate with ethyl bromoacetate, on hydrolysis gave cyclooctan-1-one-2-acetic acid. This acid on refluxing with seven different primary aromatic amines furnished substituted pyrrol-2-ones.
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