The use of Doppler vascular resistance in the early diagnosis of chronic kidney disease progression in patients with renal cell carcinoma

Pasichnyk Serhiy, Mytsyk Yulian, Hreschukh Lilia, Kowal P., Pietrus M., Borzhiievskyi A. Ts., Lychkovsky Оlexander. The use of Doppler vascular resistance in the early diagnosis of chronic kidney disease progression in patients with renal cell carcinoma. Journal of Education, Health and Sport. 2022;12(1):385-394. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.01.033

https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.01.033

https://zenodo.org/record/6412675

The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 1, 2021. No. 32343.

Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).

Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 1 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.

Przypisane dyscypliny naukowe:Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).

 © The Authors 2022;

This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland

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provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 15.12.2021. Revised: 25.12.2021. Accepted: 31.01.2022.

The use of Doppler vascular resistance in the early diagnosis of chronic kidney disease progression in patients with renal cell carcinoma

Serhiy Pasichnyk1, Yulian Mytsyk2, Lilia Hreschukh2, P. Kowal3, M. Pietrus3,

A. Ts. Borzhiievskyi1, Оlexander Lychkovsky1

1Department of Urology, Danylo Halytsky Lviv National Medical University, Faculty of Post-Graduate Education, Lviv, Ukraine

2Department of Urology, Lviv Regional Clinical Hospital, Lviv, Ukraine

3Department of Urology, Wojewódzki Szpital Specjalistyczny, Wroclaw, Poland

Abstract

Development and progression of chronic kidney disease (CKD) in patients with renal cell carcinoma (RCC) after radical nephrectomy remains an extremely pressing contemporary issue.

Postoperative changes of the ultrasound resistance index (RI) in the contralateral kidney not affected by the tumor after surgical treatment of RCC, as well as correlations between changes in IR and in glomerular filtration rate (GFR) remain far from being comprehensively investigated.

The RI changes in the parenchyma of the intact (unaffected by the tumor) kidney before and after surgical treatment for RCC, and establishing correlations between RI changes and creatinine-dependent GFR remain unexplored issues.

Objective. To assess the correlation between RI and GFR in the kidney not affected by the RCC before and after radical nephrectomy.

Materials and methods. The study enrolled 49 patients. Group I included 37 patients with an initial diagnosis of RCC (on the right), Stage III of the disease, and without signs of chronic renal failure (GFR was ≥ 90 ml/min/1.73 m2).

In patients with RCC, six months after surgery, the RI increase in the contralateral kidney unaffected by the tumor was significantly associated with a significant reduction in GFR. Thus, RI can be potentially used to predict the development of CKD in this patient population.

Key words: chronic kidney disease; renal cell carcinoma; radical nephrectomy; chronic renal failure