PsPM-FSS7B: Inhibiting human aversive memory by transcranial theta-burst stimulation to primary sensory cortex
- 1. University of Zurich
- 2. University of Zurich; University College London; University of Bonn
Description
This dataset includes skin conductance response (SCR), electromygoram (EMG), and pupil size response (PSR) measurements. Also included are CS and US information, keypress responses, keypress response times and key correctness. The dataset contains data from 68 healthy unmedicated participants (34 females) participating in a classical (Pavlovian) discriminant delay fear conditioning task. Simple and complex CS are deliverd to the intermediate phalanges of the index and middle fingers of the nondominant hand. Simple stimulis are stimulations to either index or middle finger, complex stimulis are stimulations of different temporal structure to both index and middle fingers. CS intensity is set to a perceivable but not unpleasant level. US is a train of electric square pulses delivered with a constant current stimulator (Digitimer DS7A, Digitimer, Welwyn Garden City, UK) on participants' dominant forearm through a pin-cathode/ring-anode configuration. SOA betwen the CS and US is 3.5 s. The ITI is randomly determined on each trial to be 7, 9, or 11 s. The study included fear acquisition (day 1), recall and retest sessions (day 2). Participants are divided into experimental and control groups, where experimental group received continuous theta-burst stimulation on primary somatosensory cortex contralateral to the CS hand immediately prior to fear acquisition, and control group received the same stimulation to the primary somatosensory cortex ipsilateral to the CS hand. For SCR data from the acquisition session, there are 62 datasets (28 experimental, 34 control), and for PSR, 37 datasets (20 experimental, 17 control). For EMG data from the recall session, there are 52 datasets (25 experimental, 27 control). For SCR data from the retest session, there are 56 datasets (27 experimental, 39 control), and for PSR, 42 datasets (22 experimental, 20 control).
Files
Data.zip
Additional details
Related works
- Is supplement to
- Journal article: 10.1016/j.biopsych.2022.01.021https://doi.org/10.1016/j.biopsych.2022.01.021 (DOI)
Funding
- Distributed fear learning systems in the human brain 320030_149586
- Swiss National Science Foundation
- Effects of acute stress on social behavior: Combining model-based neuroeconomics and social-affective neuroscience 100019L_173248
- Swiss National Science Foundation
- BRAINCODES – Brain networks controlling social decisions 725355
- European Commission
- ActionContraThreat – Action selection under threat: the complex control of human defense 816564
- European Commission