Search for Potent Anthelmintics. Part IX : 4-Substituted-1-Piperazinylcarbonyl Acrylic/Propionic/Nitro Benzoic Acids

Department of Chemistry, Lucknow University, Lucknow-226 007

Manuscript received 1 February 1978, revised 2 May 1978, accepted 8 July 1978

Condensation of N-alkyl or aryl piperazine with maleic, succinic and 3 or 4-nitro phthalic anhydrides in the presence of acetone or benzene yielded β-(4-alkyl or aryl-1-piperazinyl-carbonyl) acrylic/propionic acids and 2-(4-alkyl or aryl-1-pipera­zinylcarbonyl)-3 or 4-nitro benzoic acids respectively.