Synthesis of Aryloxy/Aryl Acetyl Thiosemicarbazides, Substituted 1,3,4-Oxadiazoles, 1 ,3,4-Thia- diazoles, 1 ,2,4-Triazoles and Related Compounds as Potential Fungicides

Chemistry Department, Gorakhpur University, Gorakhpur-273 001

Manuscript received 22 June 1981, accepted 28 April 1982

Twelve 1-aryloxy/aryl acetyl-4-aryl thiosemicarbazides, twelve 2-arylamino-5- aryloxy/aryl methyl-1,3,4-oxadiazoles, eleven 2-arylamino-5-aryloxy/aryl methyl-1,3,4- thiadiazoles, twelve 3-aryloxy/aryl methyl-4-aryl-5-mercapto-1,2,4-triazoles, three methyI-(3-aryloxymethyl-4-aryl-1,2,4-triazol-5-yl)-sulphides, three bis-(3-aryloxymethyl- 4-aryl-1,2,4-triazol-5-yl)-disulphides and six bis-(3-aryloxy/aryl methyl-4-aryl-1,2,4- triazol-5-yl)-alkylene disulphides were prepared. Forty nine compounds have been screened against A. niger and H. oryzae And were found to possess moderate to fairly good antifungal activity.