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Published January 4, 2022 | Version 1
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Supplementary Figures, Files and Datasets: Reduction of Metastasis via Epigenetic Modulation in a Murine Model of Metastatic Triple Negative Breast Cancer (TNBC)

Creators

  • 1. Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD 57107, USA; 2DBEST, Sioux Falls, SD 57107, USA
  • 2. Cancer Biology & Immunotherapies, Sanford Research, Sioux Falls, SD 57104, USA; Department of Surgery, University of South Dakota Sanford School of Medicine, Sioux Falls, SD 57105, USA; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 57006, USA
  • 3. Cancer Biology & Immunotherapies, Sanford Research, Sioux Falls, SD 57104, USA
  • 4. Functional Genomics and Bioinformatics Core, Sanford Research, Sioux Falls, SD 57104, USA
  • 5. Cancer Biology & Immunotherapies, Sanford Research, Sioux Falls, SD 57104, USA; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 57006, USA

Contributors

Contact person:

Data collector:

  • 1. Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD 57107, USA; 2DBEST, Sioux Falls, SD 57107, USA
  • 2. Cancer Biology & Immunotherapies, Sanford Research, Sioux Falls, SD 57104, USA; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 57006, USA

Description

*denotes Co-First Authorship

SuppFile1_Figures.docx: (Updated) Supplementary File 1 Methods and Figures; Full bioinformatics methods and supplementary figures., SuppFile2_DAVID_4SCvsControl_70DEGs.xlsx; DAVID Annotation 4SC-202 vs Control 70 DEGs: Full functional annotation clustering results from DAVID Bioinformatics Resource for the 4SC-202-induced, consensus differentially expressed genes., 
SuppFile3_DAVID_4SCvsVori_33DEGs.xlsx; DAVID Annotation 4SC-202 vs Control 33 DEGs: Full functional annotation clustering results from DAVID Bioinformatics Resource for the 4SC-202 versus Vorinostat consensus differentially expressed genes., 
SuppFile4_IPA_70_Enrichment_Cannonical_pathways.xls; IPA Canonical Pathways Enrichment 70 DEGs: Full Ingenuity Pathway Analysis (IPA) canonical pathways enrichment results for the 4SC-202-induced, consensus differentially expressed genes., SuppFile5_IPA_33_Summary.pdf; Supplementary File 5 - IPA Summary of 4SC-202 vs Vorinostat 33 DEGs: Ingenuity Pathway Analysis (IPA) summary of the enrichment results for the 4SC-202-induced, consensus differentially expressed genes against Vorinostat., SuppFile6_ExperimentRINNumbers.pdf; Supplementary File 6 - RNA Integrity Numbers: RNA extraction quality control step, one of the various steps of quality control within the RNA-sequencing workflow. These RNA Integrity numbers are from the Agilent 2100 Bioanalyzer that looks for RNA contamination and degradation., SuppFile7_4SCvsControl_allDEGs.xlsx; Workflow results including all DEGs for 4SC-202 vs Control: Full excel file that contains all of the DEGs from the results of all workflows for 4SC-202.

Files

SuppFile5_IPA_33_Summary.pdf

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