Synthesis of Azabicyclo[3.3.1 ]nonanes and Dibenzo[b,d]pyrans from 3-Aryl-2,4-dicarboethoxy-5-hydroxy-5-methyl-cyclohexanones as Potential Antimicrobial Agents

Department of Chemistry, Faculty of Science, University of Mansoura, Mansoura, Egypt

Manuscript received 19 January 1988, revised 27  May 1988, accepted 2 August 1988

Double Mannich reaction or 1a, c with formalin and benzylamine or cyclohexylamine gave 3-azabicyclo [3 3.1] nonane derivatives (2a, b), while  the Pechmann reaction of 1a, c gave the dlbenzopyrans (4, 5). The structures of the compounds have been confirmed by ir, pmr and mass spectral data.