Synthesis of some 2-Aryl-3-(2-imino-4-thiazolidinon-3-yl)-thiazolidin-4-ones, 2-Aryl-3-(2-thiohydantoin-3-yl)- thiazolidin-4-ones and 2-Amino-4-arylthiazolo- [ 4,3-b ]-1, 3,4-thiadiazoles as Possible Bactericides

Department of Chemistry, University of Gorakhpur, Gorakhpur-273 009
Manuscript received 13 February 1990, revised 19 October 1990, accepted 7 March 1991

2 Aryl-3-(2-imino-4 thiazolidinon-3-yl)thiazolidin 4 ones (2a —g), 2 aryl-3-(2- thiohydantoin 3-yl)thiazolidin-4-ones (3a — g) and 2-amino 4- arylthiazolo [4,3- b]-1 3,4- thiadiazoles (4a —g) have been obtained by cyclisation of 2-aryl 3 thiocarbanilido-4- thiazolidinones (I) with chloroacetic acid in methanol, pyridine and concentrated sulphuric acid respectively All the compounds have been assayed for their antibac­terial activity against the bacteria Staphylococcus aureus and Bacillus subtilts.