Evaluation of Anti-cancer Drugs based on Natural Products

Cancer is not just a disease; It is a complex of diseases that leads to abnormal physiology, metabolism and living life with abnormal cell growth and proliferation. Cancer is one of the most life-threatening diseases and causes high mortality in the world. The use of natural compounds has attracted a lot of attention due to its cheapness, acceptance, acceptance and public availability in order to prevent and control cancer. Is. Natural compounds such as curcumin, quercetin, lycopene and isosanates and their effects such as antioxidant anti-stress effects, cell cycle arrest, induction of apoptosis and regulation of angiogenesis have been studied. These compounds play a major role in chemotherapy drugs and targeting proliferating cells. Several natural compounds have been introduced in the clinical trial and pre-clinical trials for the treatment of cancer, and several drugs, including taxol, doxorubicin, and captopcin, have been licensed for use. Discovering and sourcing drugs from natural compounds such as plants, seas and organisms has always faced serious challenges. Because these materials are produced in very small quantities and often have a complex structure, the extraction and synthesis of natural compounds has significant limitations. Many of these natural compounds are high molecular weight molecules with complex structures that do not have desirable pharmacokinetic properties; Therefore, they need to be optimized. Structural simplification and optimization of drug compounds has led to the introduction of effective drug compounds. It is hoped that in the future, by using screening methods and the use of artificial intelligence, more effective compounds in this field will be discovered and identified.