eQTL Catalogue
Published February 27, 2022 | Version v1
Dataset Open

Immune disease variants modulate gene expression in regulatory CD4+ T cells

Creators

  • 1. Wellcome Sanger Institute, Cambridge, UK
  • 2. Wellcome Sanger Institute, Cambridge, UK;New York Genome Center, New York, NY, USA
  • 3. NHS Blood and Transplant, Oxford, UK; Radcliffe Department of Medicine, University of Oxford, UK
  • 4. Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, UK
  • 5. Wellcome Sanger Institute, Cambridge, UK;Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, UK
  • 6. Wellcome Sanger Institute, Cambridge, UK; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, UK
  • 7. Wellcome Sanger Institute, Cambridge, UK;Institute of Computer Science, University of Tartu, Tartu, Estonia
  • 8. European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, UK

Description

We mapped genetic regulation (QTL) of gene expression and chromatin activity in Tregs and we identified 133 colocalizing loci with immune disease variants.
For the time being, the preprint DOI: 10.1101/654632

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