Elegant synthesis of novel pyrroles and dipyrrylmethane of biosynthetic importance

Department of Chemistry, University of Allahabad, Allahabad-21 1 002, India

E-mail : singhvandanasingh@rediffmail.com

Manuscript received 30 May 2001. revised 12 November 2001, accepted 21 March 2002

Ethyl 4-ethoxycarbonylinethyl-3,5-dimethylpyrrole-2-carboxylate (1) has been synthesized by extension and modification of Knorr pyrrole synthesis. Its acetoxymethyl derivative (2) has also been synthesized. Diethyl 3,3'-bis(ethoxycarbonylmethyl)-4,4^'-dimethyl­2,2'-dipyrrylmethane-5,5¹-dicarboxylate has been synthesized by self-condensation of 2.