Synthesis of some novel 4-thiazolidinone compounds and their application as potential antimicrobial agent

Department of Chemistry, B. K. M. Science College, Valsad-396 001, Gujarat, India

Manuscript received 14 July 2005, revised 4 January 2006, accepted 28 June 2006

3-Chloro-1-[5' -hydroxy-2' -(phenyldiazenyl) phenyll-4-[2" -hydroxy-5" -(1"' ,3'" -benzothiazol-2"' -yl-diazenyl)phenyl)-2-azetidinone (4a-p),3-[5'-hydroxy-2'-(phenyldiazenyl)phenyl]-2-[2" -hydrox)·-5" -(1"' ,3'" -benzothiazol-2"' -yl-diazenyl) phenyl)- 4-thiazolidinone (Sa-p) and 3-[5' -hydroxy-2' (phenyldiazenyl)phenyl)-2-[2" -hydroxy-5" -(1 '" ,3"' -benzothiazol -2'" -yldiazenyl) phenyl)-4 methylthiazolidinone have been synthesized from their Schiff bases (3a-p). They have been screened for their antimicrobial activities.