Base-catalysed cyclocondensation of α,α' -bis(arylmethylene)cyclohexanones with thiourea: Formation of E-8-(arylmethylene)-4-aryl-1,2,3,4,5,6,7,8- octahydrobenzo[d]pyrimidine-2-thiones

Department of Chemistry. Jadavpur University, Kolkata-700 032, India

E-mail : mallikak52@yahoo.co.in

Manuscript received 11 November 2008, accepted 23 December 2008

Base-catalysed cyclocondensation of α,α'-bis(arylmetbylene)cyclobexanones with thiourea has been found to generate E-8-(arylmethylene)-4-aryl-1,2,3,4,5,6, 7,8-octahydrobenzo[d]pyrimidine-2-thiones in high yield, the structures of which have been established from their spectral data. However, corresponding cyclopentanones were found to be unreactive under similar reaction condition.