New method of isolation of piperine from Piper retrofractum Vahl.

Chemistry Department, CMP Degree College (Constituent College of University of Allahabad),

Allahabad-211 002, Uttar Pradesh, India

E-mail : archanaapandey@yahoo.co.in, ravi_ biochem05@rediffmail.com, santoo 1976@rediffmail.com, prashant_ babita@yahoo.com

Manuscript received 20 September 2011, revised 01 June 2012, accepted 11 July 2012

Piperine is a major bioactive constituent of the plants of piperaceae family having plethora of therapeutic application. It enhances the bioavailability of many nutraceuticals and drugs. It is generally isolated from Piper nigrum (black pepper) with the help of ethanol-KOH, glacial acetic acid-chloroform, dichloromethane-ether etc. The present work describes a new method of extraction of piperine from fruits of \(Piper\) \(retrofractum\) Vahl. by methanol-water in an easy, efficient and cost effective manner.