Essentials of oral cancer
Creators
- 1. Department of Basic Biomedical Sciences, University of Talca (UTALCA) Talca, Maule Region, Chile
Description
Oral cancer is one of the 10 most common cancers in the world, with a delayed clinical detection, poor prognosis, without specific biomarkers for the disease and expensive therapeutic alternatives. This review aims to present the fundamental aspects of this cancer, focused on squamous cell carcinoma of the oral cavity (OSCC), moving from its definition and epidemiological aspects, addressing the oral carcinogenesis, oral potentially malignant disorders, epithelial precursor lesions and experimental methods for its study, therapies and future challenges. Oral cancer is a preventable disease, risk factors and natural history is already being known, where biomedical sciences and dentistry in particular are likely to improve their poor clinical indicators.
Files
ijcep0008-11884.pdf
Files
(625.7 kB)
Name | Size | Download all |
---|---|---|
md5:0bda121a90f14d31ec026baf82d98bc0
|
625.7 kB | Preview Download |
Additional details
References
- Lingen MW, Kalmar JR, Karrison T and Speight PM. Critical evaluation of diagnostic aids for the detection of oral cancer. Oral Oncol 2008; 44: 10-22
- Barnes L, Organization WH and Cancer IAfRo. Pathology and genetics of head and neck tumours. World Health Organization 2005
- Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009; 45: 309-316
- Dissanayaka WL, Pitiyage G, Kumarasiri PV, Liyanage RL, Dias KD and Tilakaratne WM. Clinical and histopathologic parameters in survival of oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 113: 518-525
- Koontongkaew S. The tumor microenvironment contribution to development, growth, invasion and metastasis of head and neck squamous cell carcinomas. J Cancer 2013; 4: 66-83
- IARC Working Group on the Evaluation of Carcinogenic Risk to Humans. Smokeless tobacco and some tobacco-specific N-nitrosamines. World Health Organization 2007
- Gandini S, Botteri E, Iodice S, Boniol M, Lowenfels AB, Maisonneuve P and Boyle P. Tobacco smoking and cancer: a meta-analysis. Int J Cancer 2008; 122: 155-164
- Marron M, Boffetta P, Zhang ZF, Zaridze D, Wunsch-Filho V, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Schwartz SM, Rudnai P, Purdue MP, Olshan AF, Eluf-Neto J, Muscat J, Morgenstern H, Menezes A, McClean M, Matos E, Mates IN, Lissowska J, Levi F, Lazarus P, La Vecchia C, Koifman S, Kelsey K, Herrero R, Hayes RB, Franceschi S, Fernandez L, Fabianova E, Daudt AW, Dal Maso L, Curado MP, Cadoni G, Chen C, Castellsague X, Boccia S, Benhamou S, Ferro G, Berthiller J, Brennan P, Moller H and Hashibe M. Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk. Int J Epidemiol 2010; 39: 182-196
- Lee YC, Marron M, Benhamou S, Bouchardy C, Ahrens W, Pohlabeln H, Lagiou P, Trichopoulos D, Agudo A, Castellsague X, Bencko V, Holcatova I, Kjaerheim K, Merletti F, Richiardi L, Macfarlane GJ, Macfarlane TV, Talamini R, Barzan L, Canova C, Simonato L, Conway DI, McKinney PA, Lowry RJ, Sneddon L, Znaor A, Healy CM, McCartan BE, Brennan P and Hashibe M. Active and involuntary tobacco smoking and upper aerodigestive tract cancer risks in a multicenter case-control study. Cancer Epidemiol Biomarkers Prev 2009; 18: 3353-3361
- Lee J, Taneja V and Vassallo R. Cigarette smoking and inflammation: cellular and molecular mechanisms. J Dent Res 2012; 91: 142-149.
- Parise O. Câncer de boca: aspectos básicos e terapêuticos. Sarvier 2000
- Choudhari SK, Chaudhary M, Gadbail AR, Sharma A and Tekade S. Oxidative and antioxidative mechanisms in oral cancer and precancer: a review. Oral Oncol 2014; 50: 10-18
- Reidy J, McHugh E and Stassen LF. A review of the relationship between alcohol and oral cancer. Surgeon 2011; 9: 278-283
- Dalianis T. Human papillomavirus and orop- haryngeal cancer, the epidemics, and significance of additional clinical biomarkers for prediction of response to therapy (Review). Int J Oncol 2014; 44: 1799-1805
- Kang H, Kiess A and Chung CH. Emerging biomarkers in head and neck cancer in the era of genomics. Nat Rev Clin Oncol 2015; 12: 11-26
- Neville BW. Oral and Maxillofacial Pathology. Saunders/Elsevier, 2009
- Tanaka T and Ishigamori R. Understanding carcinogenesis for fighting oral cancer. J Oncol 2011; 2011: 603740
- Fukuda M, Ohmori Y and Sakashita H. The Role of Tumor Microenvironment in Oral Cancer. In: Biswas S, editors. Tumor Microenvironment and Myelomonocytic Cells. InTech; 2012
- Curry JM, Sprandio J, Cognetti D, Luginbuhl A, Bar-ad V, Pribitkin E and Tuluc M. Tumor microenvironment in head and neck squamous cell carcinoma. Semin Oncol 2014; 41: 217-234
- Feller LL, Khammissa RR, Kramer BB and Lemmer JJ. Oral squamous cell carcinoma in relation to field precancerisation: pathobiology. Cancer Cell Int 2013; 13: 31
- Merlo LM, Pepper JW, Reid BJ and Maley CC. Cancer as an evolutionary and ecological process. Nat Rev Cancer 2006; 6: 924-935
- Hanahan D and Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70
- Pickup MW, Mouw JK and Weaver VM. The extracellular matrix modulates the hallmarks of cancer. EMBO Rep 2014; 15: 1243-1253
- Rivera C and Venegas B. Histological and molecular aspects of oral squamous cell carcinoma (Review). Oncol Lett 2014; 8: 7-11
- Cavallo F, De Giovanni C, Nanni P, Forni G and Lollini PL. 2011: the immune hallmarks of cancer. Cancer Immunol Immunother 2011; 60: 319-326
- Cavallo F, De Giovanni C, Nanni P, Forni G and Lollini PL. 2011: the immune hallmarks of cancer. Cancer Immunol Immunother 2011; 60: 319-326
- van der Waal I. Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncol 2009; 45: 317-323
- Warnakulasuriya S, Johnson NW and van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med 2007; 36: 575-580
- Scully C, Bagan JV, Hopper C and Epstein JB. Oral cancer: current and future diagnostic techniques. Am J Dent 2008; 21: 199-209
- Scully C, Bagan JV, Hopper C and Epstein JB. Oral cancer: current and future diagnostic techniques. Am J Dent 2008; 21: 199-209
- Cancer Genome Atlas Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature 2015; 517: 576-582
- Yellowitz JA, Horowitz AM, Drury TF and Goodman HS. Survey of U.S. dentists' knowledge and opinions about oral pharyngeal cancer. J Am Dent Assoc 2000; 131: 653-661
- Bagan J, Sarrion G and Jimenez Y. Oral cancer: clinical features. Oral Oncol 2010; 46: 414-417
- Markopoulos AK. Current aspects on oral squamous cell carcinoma. Open Dent J 2012; 6: 126-130
- Patel SG and Shah JP. TNM staging of cancers of the head and neck: striving for uniformity among diversity. CA Cancer J Clin 2005; 55: 242-258; quiz 261-242, 264
- Elashoff D, Zhou H, Reiss J, Wang J, Xiao H, Henson B, Hu S, Arellano M, Sinha U, Le A, Messadi D, Wang M, Nabili V, Lingen M, Morris D, Randolph T, Feng Z, Akin D, Kastratovic DA, Chia D, Abemayor E and Wong DT. Prevalidation of salivary biomarkers for oral cancer detection. Cancer Epidemiol Biomarkers Prev 2012; 21: 664-672
- Zhang L, Poh CF, Williams M, Laronde DM, Berean K, Gardner PJ, Jiang H, Wu L, Lee JJ and Rosin MP. Loss of heterozygosity (LOH) profiles--validated risk predictors for progression to oral cancer. Cancer Prev Res (Phila) 2012; 5: 1081-1089
- Rivera C. Opportunities for biomarkers with potential clinical use in oral cancer. Medwave 2015; 15: e6186
- Rheinwald JG and Beckett MA. Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas. Cancer Res 1981; 41: 1657-1663
- Zhao M, Sano D, Pickering CR, Jasser SA, Henderson YC, Clayman GL, Sturgis EM, Ow TJ, Lotan R, Carey TE, Sacks PG, Grandis JR, Sidransky D, Heldin NE and Myers JN. Assem- bly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites. Clin Cancer Res 2011; 17: 7248-7264
- Kotowski U, Heiduschka G, Brunner M, Erovic BM, Martinek H and Thurnher D. Arsenic trioxide enhances the cytotoxic effect of cisplatin in head and neck squamous cell carcinoma cell lines. Oncol Lett 2012; 3: 1326-1330
- Cullen KJ, Newkirk KA, Schumaker LM, Aldosari N, Rone JD and Haddad BR. Gluta- thione S-transferase pi amplification is associated with cisplatin resistance in head and neck squamous cell carcinoma cell lines and primary tumors. Cancer Res 2003; 63: 8097-8102
- Schneider GB, Kurago Z, Zaharias R, Gruman LM, Schaller MD and Hendrix MJ. Elevated focal adhesion kinase expression facilitates oral tumor cell invasion. Cancer 2002; 95: 2508-2515
- Gioanni J, Fischel JL, Lambert JC, Demard F, Mazeau C, Zanghellini E, Ettore F, Formento P, Chauvel P, Lalanne CM, et al. Two new human tumor cell lines derived from squamous cell carcinomas of the tongue: establishment, characterization and response to cytotoxic treatment. Eur J Cancer Clin Oncol 1988; 24: 1445-1455
- Erdem NF, Carlson ER, Gerard DA and Ichiki AT. Characterization of 3 oral squamous cell carcinoma cell lines with different invasion and/or metastatic potentials. J Oral Maxillofac Surg 2007; 65: 1725-1733
- Lehmann B. HaCaT cell line as a model system for vitamin D3 metabolism in human skin. J Invest Dermatol 1997; 108: 78-82
- Rivera CA, Droguett DA, Kemmerling U and Venegas BA. Chronic restraint stress in oral squamous cell carcinoma. J Dent Res 2011; 90: 799-803
- Vitale-Cross L, Czerninski R, Amornphimoltham P, Patel V, Molinolo AA and Gutkind JS. Che- mical carcinogenesis models for evaluating molecular-targeted prevention and treatment of oral cancer. Cancer Prev Res (Phila) 2009; 2: 419-422
- Rivera C. 4NQO carcinogenesis: A model of oral squamous cell carcinoma. Int J Morphol 2012; 30: 309-314
- Ensley JF, Gutkind S, Jacobs JA and Lippman S. Head and Neck Cancer: Emerging Perspectives. Elsevier Science: 2003
- Mehrotra R and Gupta DK. Exciting new advances in oral cancer diagnosis: avenues to early detection. Head Neck Oncol 2011; 3: 33
- Huang SH and O'Sullivan B. Oral cancer: Current role of radiotherapy and chemotherapy. Med Oral Patol Oral Cir Bucal 2013; 18: e233-240
- Rivera C. The challenge of the state of susceptibility to oral cancer. J Oral Res 2015; 4: 8-9
- Huber MA and Tantiwongkosi B. Oral and oropharyngeal cancer. Med Clin North Am 2014; 98: 1299-1321
- Yao M, Epstein JB, Modi BJ, Pytynia KB, Mundt AJ and Feldman LE. Current surgical treatment of squamous cell carcinoma of the head and neck. Oral Oncol 2007; 43: 213-223
- Guneri P and Epstein JB. Late stage diagnosis of oral cancer: components and possible solutions. Oral Oncol 2014; 50: 1131-1136
- Kowalski LP and Carvalho AL. Natural history of untreated head and neck cancer. Eur J Cancer 2000; 36: 1032-1037
- Viet CT and Schmidt BL. Biologic mechanisms of oral cancer pain and implications for clinical therapy. J Dent Res 2012; 91: 447-453
- Petersen PE. Oral cancer prevention and control--the approach of the World Health Orga- nization. Oral Oncol 2009; 45: 454-460
- Brocklehurst P, Kujan O, O'Malley LA, Ogden G, Shepherd S and Glenny AM. Screening programmes for the early detection and prevention of oral cancer. Cochrane Database Syst Rev 2013; 11: Cd004150