Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress

Olekshij P. V. Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress. Journal of Education, Health and Sport. 2021;11(11):67-72. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.11.005

https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.11.005  

https://zenodo.org/record/5668663

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

© The Authors 2021;

This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland

Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,

provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.

(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 10.10.2021. Revised: 22.10.2021. Accepted: 10.11.2021.

UDC: 616.314.18-002.4:612.176:616.155.3:615.015.8]-092.9

Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress

P. V. Olekshij

Lviv Medical Institute

Abstract

The aim of our study was to determine the phagocytic activity of leukocytes and nitrosine tetrazolium test (NST - test) in the dynamics of experimental periodontitis (EP) and immobilization stress (IS). It is established in the work that the indicators studied by us, namely phagocytic number, phagocytic index and NST - test increase on the 3 rd, 5 th and 15 th days of our experiment. The above tests have a high diagnostic value and allow to characterize the degree of activity of the inflammatory process and determine the participation of individual parts of the body's defense mechanisms. The obtained results make it possible to express the opinion that polymorphonuclear leukocytes take an active part in the formation of EP and IS, as well as indicate the stimulation of metabolic processes in leukocytes.

Key words: periodontitis; stress; polymorhonuclear leucocytes; nonspecific resistance.