FORMULATION AND EVALUATION OF LEVOFLOXACIN AN ANTIBIOTIC DRUG INTO ORAL DISPERSIBLE TABLETS

Levofloxacin is used to treat a variety of bacterial infections. This medication belongs to a class of drugs known as quinolone antibiotics. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

Oral disintegrating tablets are solid single unit dosage forms that are placed on tongue, allowed to disperse or dissolve in saliva without the need of water, frequently releasing of the drug for quick onset of action. Oral disintegrating tablets are well accepted by wide range of population especially as pediatric and geriatric patients

who have difficulty in swallowing of conventional dosage forms. Some drugs areabsorbed from mouth, pharynx and esophagus as saliva passes down to stomach.

KEY WORDS: quinolone, levofloxacin, antibiotic, esophagus, pharynx,