Published April 20, 2015
| Version v1
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The Antidiabetic Drug Metformin and Male Reproductive Function: An Overview
Creators
- 1. CICS – UBI – Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal, Department of Microscopy, Laboratory of Cell Biology and Unit for Multidisciplinary Research in Biomedicine, Abel Salazar Institute of Biomedical Sciences, University of Porto – UMIB/ICBAS/UP, Portugal.
- 2. Department of Microscopy, Laboratory of Cell Biology and Unit for Multidisciplinary Research in Biomedicine, Abel Salazar Institute of Biomedical Sciences, University of Porto – UMIB/ICBAS/UP, Portugal, Centre for Reproductive Genetics Professor Alberto Barros, Porto, Portugal
- 3. CICS – UBI – Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal
- 4. CICS – UBI – Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal, Department of Microscopy, Laboratory of Cell Biology and Unit for Multidisciplinary Research in Biomedicine, Abel Salazar Institute of Biomedical Sciences, University of Porto – UMIB/ICBAS/UP, Portugal
Description
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia resulting from defects in insulin action, insulin secretion, or both. These defects lead to disturbances in carbohydrates, lipid and protein metabolism causing systemic complications and co-morbidities, particularly in renal and cardiovascular systems. This disease is reaching pandemic proportions and a recent report estimated that more than 300 million of
people worldwide already have DM and, alarmingly, some projections
suggest that the number of diabetic patients will reach nearly 600 million by the year 2035.
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