Published February 10, 2016 | Version v1
Journal article Open

3DBIONOTES: A unified, enriched and interactive view of macromolecular information

Description

With the advent of high throughput techniques like Next Generation Sequencing, the amount of biological
information for genes and proteins is growing faster than ever. Structural information is also rapidly
growing, especially in the cryo Electron Microscopy area. However, in many cases, the proteomic and
genomic data are spread in multiple databases and with no simple connection to structural information.
In this work we present a new web platform that integrates EMDB/PDB structures and UniProt
sequences with different sources of protein annotations. The application provides an interactive interface
linking sequence and structure, including EM maps, presenting the different sources of information at
sequence and structural level. The web application is available at http://3dbionotes.cnb.csic.es.

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Additional details

Funding

ELIXIR-EXCELERATE – ELIXIR-EXCELERATE: Fast-track ELIXIR implementation and drive early user exploitation across the life-sciences. 676559
European Commission
CORBEL – Coordinated Research Infrastructures Building Enduring Life-science services 654248
European Commission
EGI-Engage – Engaging the EGI Community towards an Open Science Commons 654142
European Commission