Prevalence of Type II Diabetes Mellitus in Patients with Chronic HCV

Abstract: 

Objective: The main aim of this study was to find the prevalence of type II diabetes mellitus in patients with chronic HCV.  

Place and Duration of Study: This study was carried out in a duration of 8 months from April 2019 to December 2019.  

Materials and Methods: A total of 200 patients were selected for this study between the ages of 18-60 years. Both male and female genders with a positive history of HCV infection and no past history of diabetes mellitus were included in this study. Qualitative PCR was done for the detection of HCV. Patients with fasting blood glucose levels greater than 126mg/dl were labelled as diabetics. A pre designed proforma was used for collection of the data. Informed consent was taken from all the patients. Ethical committee approval was taken. Data was analyzed using SPSS using version 20.  

Results: 200 patients with a chronic history of HCV were included in this study. Among these 80 (40%) were female patients and 120 (60%) were male patients. Mean age of the patients was 47.25 years. Diabetes mellitus was seen in 56% of the cases and it was 28% proportionally. Signs of diabetes mellitus were seen in 30 patients with a positive family history constituting 53.57% of the total. 0.001 was the significant p-value. BMI<25kg/m2 was seen in 14 patients while BMI > 25 was seen in 42 patients.  

Conclusion: Diabetes mellitus type II has been reported repeatedly in already diagnosed patients of HCV. Positive family history and increased BMI above 25 are also contributing factor having strong association with type II diabetes.