Extracellular enzymes and βeta-lactamase screening of bacterial isolates cultured from urine samples of immunocompromised women

Enzymes intricate by organisms are used to inactivate and destroy antibiotics. This study determined some virulence factors elaborated by the bacterial isolates cultured from urine samples of HIV seropositive pregnant women that attended antenatal clinic of the Ondo State Specialist Hospital, Akure. Screening for extracellular enzymes and extended spectrum beta lactamase (ESBL) of the isolate was carried out using standard method and disk approximation method respectively. The extracellular enzymes such as lipase, protease and DNase were detected in the three bacterial genera used. ESBL was found in S. aureus and E. coli. The study concluded that most of the bacterial isolates cultured from urine samples of HIV seropositive pregnant women in the study area were found to have these virulence factors.