ADVANTAGES OF HIGH OLEIN SUNFLOWER OIL OVER PALM OIL ACCORDING TO BIOCHEMICAL RESEARCH RESULTS

Gozhenko A. I., Levitsky A. P., Stepan V. T., Pustovoit I. P., Badiuk N. S., Maslyukov A. K. ADVANTAGES OF HIGH OLEIN SUNFLOWER OIL OVER PALM OIL ACCORDING TO BIOCHEMICAL RESEARCH RESULTS. Pharmacologyonline. 2020. vol.2. 293-301. ISSN 18278620

https://zenodo.org/record/4013906

ADVANTAGES OF HIGH OLEIN SUNFLOWER OIL OVER PALM OIL ACCORDING TO BIOCHEMICAL RESEARCH RESULTS

Gozhenko A.I.1, Levitsky A.P.2, Stepan V.T.3, Pustovoit I.P.4, Badiuk N.S.1, Maslyukov A.K.5

1State Enterprise “Ukrainian Scientific Research Institute of Transport Medicine of Health of Ukraine”, Odesa, Ukraine

2Odessa National Academy of Food Technologies, Odesa, Ukraine

3Bukovinian State Medical University, Chernivtsi, Ukraine

4MI "Odessa Regional Clinical Hospital", Odesa, Ukraine

5Odessa International Medical University, Odesa, Ukraine

Abstract

Aim: to compare the effect of palm and high oleic sunflower oil (HOSO) on the biochemical parameters of the body of rats.

Methods: rats received food containing 15% palm oil or 15% HOSO for 41 days. The activity of elastase, urease, lysozyme, catalase, level of MDA determined in the tissues. The antioxidant-prooxidant index of API was calculated from the ratio of catalase activity and MDA level, and dysbiosis level was calculated from the ratio of relative activities of urease and lysozyme.

Results: was revealed an increase in elastase and urease activity, increase in dysbiosis level and level of MDA, decrease in the activity of catalase, lysozyme and API index, much more pronounced in animals that received palm oil.

Conclusion: high-fat diet causes the development of dysbiosis, decreased levels of protective enzymes (lysozyme and catalase) and increased levels of markers of inflammation (elastase and MDA). Palm oil has a stronger negative effect on the body. It is recommended to use high-oleic sunflower oil in food.

Keywords: high-fat diet, palm oil, high-oleic sunflower oil, dysbiosis, inflammation, lysozyme, catalase