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Published April 9, 2020 | Version v1
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CusVarDB: A tool for building customized sample-specific variant protein database from Next-generation sequencing datasets

  • 1. Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University)
  • 2. Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University) and Institute of Bioinformatics, International Technology Park

Description

CusVarDB is a windows based tool for creating a variant protein database from Next-generation sequencing datasets. The program supports variant calling for Genome, RNA-Seq and exome datasets.

This repository will provide the resultant variant peptides identified in our study and its corresponding information. The detailed information of the table is given below.

Supplementary Table 1. This table contains the resultant variant peptides along with its wild-type peptides from BT474, MDMAB157, MFM223, and HCC38 datasets. Along with mutant peptides, this section also provides additional information such as peptide-spectrum match (PSM), Protein accession, cross-correlation value from the search (Xcorr) and retention time (RT).

Supplementary Table 2.This table provides the complete details of the resultant peptides. Here the mutant and corresponding wild-type peptides are mentioned in different sheets. For a given mutant peptide its wild-type peptide and corresponding information can be mapped using the VLOOKUP function in Excel by keeping column A (Sl.No) as lookup parameter.

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CusVarDB_extended_data.zip

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Additional details

Related works

Is supplemented by
Journal article: 10.12688/f1000research.23214.1 (DOI)