A Rarely Adverse Reaction Case of Combined Diphtheria, Tetanus, Pertussis (DTP) Vaccination

A rarely adverse reaction case of combined diphtheria, tetanus, pertussis (DTP) vaccination was reported. The injection site in the arm of a two-year-boy presented swelling and redness, and itching four hours after having given the second dose of DTP vaccine. Meanwhile, he showed drowsiness, non-stop crying and fretfulness, and felt severe pain and soreness or tenderness in the arm. Then, his arm displayed local edema and scattered rash. The boy had a low-grade temperature fever, and came out mucous blisters in the arm, allergic rash or hives (urticatria) and angioneurotic edema one day later. However, his symptoms and conditions alleviated and improved gradually after the combined treatment of anti-infection, anti-allergy and local wet compress of a week. The child recovered fully one week later.