COMPARISON OF MEAN LIPID PROFILE BETWEEN TYPE-II DIABETICS AND NON-DIABETICS

Objective:  To compare the mean lipid profile between type-II diabetics and non-diabetics at tertiary care hospital. 

Material and methods:

This case control study was conducted at Department of Medicine, Bahawal Victoria Hospital, Bahawalpur from August 2018 to February 2019 over the period of 6 months.  Total 100 type-II diabetics having age >40 years wither male or female and duration of diabetes mellitus more than 4 years were selected.  Age and sex matched 25 non-diabetics are taken as controls. Lipid parameters were compared between diabetics and non-diabetics. 

Results:

Mean serum cholesterol level in cases and controls were 209.02±27.15 mg/dl and 182.24±49.03 mg/dl respectively.  Significantly higher mean serum cholesterol was noted in cases as compared to controls with p value 0.000.  Mean total LDL in cases was 126.82±25.63 mg/dl and in controls was 106.76±27.29 mg/dl.  Difference of mean LDL level between cases and controls was statistically significant with p value 0.000.  In cases, mean Triglyceride level was 223.54±46.98 mg/dl and in controls was 151.48±40.12 mg/dl.  Mean serum Triglyceride levels was significantly high in cases as compared to controls with p value 0.000.  Mean HDL of cases was 36.24±4.96 mg/dl and in controls was 41.24±1.55 mg/dl and the difference was statistically significant with value 0.000.

Conclusion:

Results of present showed that lipid parameters are significantly higher in type-II diabetics as compared to non-diabetics.  Retinopathy was the most common complication.

Key words:  Diabetes, lipid profile, complications