Published October 21, 2019 | Version v1
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The analysis of differentially expressed genes relevant to glycolysis in hypoxia-treated gastric cancer cells

Creators

  • 1. Institute of Cancer Research and Basic Medical Sciences of Chinese Academy of Sciences, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital

Description

   RNA sequencing was conducted to identify hypoxia-altered genes in GC cells. A total of 13,469 genes were included,  with 430 genes upregulated and 476 genes downregulated. Gene Ontology (GO) analysis indicated that hypoxia-regulated genes mainly focused in glycolysis and canonical glycolysis pathways. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that hypoxia-regulated genes were significantly correlated with glycolysis pathway.

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