Published November 11, 2015 | Version v1
Dataset Open

Simulation results and lambda value data for structural connectome based simulations of temporal lobe epilepsy surgery.

  • 1. School of Computing Science, Newcastle University
  • 2. Department of Biomedical Engineering, Korea University; Department of Brain Cognitive Sciences, Seoul National University
  • 3. Department of Molecular and Clinical Pharmacology, Institute of translational medicine, University of Liverpool
  • 4. Center for Economics and Neuroscience, University of Bonn
  • 5. School of Computing Science &Institute of Neuroscience, Newcastle University


This data file contains a number of matlab matrices holding the results of simulations carried out using structural connectome data from healthy individuals and individuals with a diagnosis of temporal lobe epilepsy (TLE). The results are in the form of either time values, representing the time at which brain regions in the simulations 'escaped' into a seizure state, or corresponding node labels which represent the region that escaped at that time. Simulations were stopped after the first three nodes escaped, and then repeated over 100 iterations. There were 39 controls and 22 left TLE patients. Simulations were also carried out for altered structural connectomes simulating surgery influence on the time taken for nodes to escape. Clinical resection (clinres), subject-specific resections (subspecres) or random resections (ranres). 'Lmdas' shows the deviation from the control average of surface areas for each region in each subject, normalised to lie between 0 and 1. 'Names' is a cell array containing the node labels for the 82 regions.


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