Three new species of Lachemilla (Rosaceae), two from Colombia and one from Peru, are described and illustrated. Lachemilla rothmaleriana is characterized by its stout stems, sericeous-villous indumentum, and wide ascending sheaths with trilobate lateral lobes. Lachemilla argentea presents a unique combination of tripartite basal leaves with an adaxial silvery villous indumentum, and decumbent branches with verticillate lobed sheaths. Finally, Lachemilla cyanea has distinctly basal reniform leaves with a blue-green color and hirsute pubescence. Phylogenetic analyses of the nuclear ribosomal cistron and multiple regions of the plastid genome revealed the allopolyploid origin of the three new taxa.