Published April 10, 2019
| Version v1.1.6
Software
Open
XYalign: Version 1.1.6
Creators
- 1. Department of Anthropology, University of Utah
- 2. Child and Family Research Institute, University of British Columbia
- 3. Department of Molecular Biology and Biochemistry, Simon Fraser University
- 4. Division of Cancer Epidemiology, National Cancer Institute, National Institutes of Health
- 5. Interdepartmental Program in Bioinformatics, UCLA
- 6. Centre for Molecular Medicine and Therapeutics, University of British Columbia
- 7. School of Biological Sciences, The University of Auckland
- 8. School of Life Sciences, Arizona State University
Description
The high degree of similarity between gametologous sequences on the sex chromosomes can lead to the misalignment of sequencing reads and substantially affect variant calling. Here we present XYalign, a new tool that (1) quickly infers sex chromosome ploidy in NGS data, (2) remaps reads based on the inferred sex chromosome complement of the individual, and (3) outputs quality, depth, and allele-balance metrics across chromosomes.
Notes
Files
XYalign-1.1.6.zip
Files
(2.5 MB)
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