Published March 29, 2019 | Version 1.0.0
Software Open

DD-DeCaF/caffeine: Version 1

  • 1. The Novo Nordisk Foundation Center for Biosustainability
  • 2. Genialis d.o.o

Description

  • A user can manually design a strain (media optimization, gene and reaction knockouts, overexpression, downregulation) on the interactive pathway map given that she can provide at least a genome-scale metabolic model that passes memote tests sufficiently as a minimal input.
  • A users can predict strain designs for a given organism and target molecule. Strain designs can be further evaluated on metabolic pathway maps.
  • A user can rely on simulations integrating all the available data in a sensible manner, for example, if a simulation is chosen for an experimental dataset that features fluxomics and metabolomics data, than reaction bounds and directionalities will be appropriately constrained.
  • A user can upload and manage models and maps on the platform.

Files

DD-DeCaF/caffeine-1.0.0.zip

Files (5.0 MB)

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Additional details

Related works

Funding

European Commission
DD-DeCaF – Bioinformatics Services for Data-Driven Design of Cell Factories and Communities 686070