Published June 30, 2017 | Version v1
Journal article Open

Recurrence of Immunotactoid Glomerulopathy with Monoclonal IgG3κ Deposits after Kidney Transplant

Creators

  • 1. Maki Sumida, Department of Nephrology and Endocrinology, University Hospital, The University of Tokyo, 7-3-1 Hongo Bunkyo, Tokyo, 113-8655, Japan,
  • 1. #S2, 215, Kavuri Hills Jubilee Hills, Hyderabad-500033, India

Description

We report a case of rapid recurrence of immunotactoid glomerulopathy (ITG) with monoclonal IgG3κ deposits in a transplanted renal graft. A 55-year-old hemodialysis male patient due to ITG underwent an ABO-incompatible living-donor kidney transplantation. Proteinuria (3.11 g/day) and increased serum creatinine (2.52 mg/dL) were detected on postoperative day (POD) 4 due to acute antibody-mediated rejection (aAMR). Even after treatment for aAMR, proteinuria increased again to 4.5 g/day because of a recurrent ITG with IgG3κ subclass deposits. He returned to maintenance hemodialysis 9 months after transplantation. 

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