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Published January 16, 2026 | Version v1
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Supplementary Data

Authors/Creators

  • 1. ROR icon City University of Hong Kong

Description

DEPRECATED 

outdated reference build (superseded). Use the current dataset at https://doi.org/10.5281/zenodo.22068981

 

 

Project Overview
This repository contains the foundational reference data and processed datasets associated with MetaTCR, a computational framework designed to standardize T-cell Receptor (TCR) repertoires and mitigate batch effects in Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) data.

MetaTCR addresses the challenge of non-biological variation by constructing a population-scale "Referenced TCR Space." This allows raw TCR repertoires to be converted into fixed-dimensional feature profiles (meta-vectors), enabling robust cross-study comparison and integration. The data provided here allows researchers to reproduce the study's benchmarking results, utilize the pre-trained reference space for new data, and explore the batch correction capabilities of the framework.

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