Next-generation vaccines and diagnostics to prevent livestock reproductive diseases of worldwide impact

Part of EU Open Research Repository
Published January 9, 2026 | Version v1
Data paper Open

Protein display of in-frame Immunoglobulin Variable Domain (IGV) for sequenced single cell pair Immunoglobulin Heavy Chain (IGHC) and Immunoglobulin Light Chain (IGLC) genes using the international ImMunoGeneTics information system (IMGT) unique numbering

Authors/Creators

  • 1. ROR icon The Pirbright Institute

Description

Sequences from single sorted B cells were compared to standardized representations of the amino acid sequences of the variable (V)-DOMAINs, including framework regions (FR1-IMGT, FR2-IMGT, FR3-IMGT, FR4-IMGT) and complementarity determining regions (CDR1-IMGT, CDR2-IMGT, CDR3-IMGT), enabling comparison to, and calculation of distance from, nearest germline sequences. Sequences in bold were successfully expressed.

Files

Table S4.pdf

Files (177.9 kB)

Name Size
md5:56619199e25dff472ad2890065a7326c
177.9 kB Preview Download

Additional details

Funding

European Commission
REPRODIVAC - Next-generation vaccines and diagnostics to prevent livestock reproductive diseases of worldwide impact 101060813
UK Research and Innovation
REPRODIVAC – Next-generation vaccines and diagnostics to prevent livestock reproductive diseases of worldwide impact 10047358