Published November 27, 2025 | Version 1.0
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Skrupskelyte etal SI code: Publication supporting code and notebooks

  • 1. ROR icon Wellcome Sanger Institute
  • 2. ROR icon University of Cambridge

Description

This repository contains R code used to produce copynumber analyses and figures for the supplementary information accompanying Skrupskelyte et al. 

Files 

qdnaseq_call_offtarget_read_cn.R - Main R script to call copynumber. 
Detailed run instructions and dependencies can be found at: https://github.com/PHJonesGroup/Skrupskelyte_etal_SI_code and also in the Readme file here
 
README.md - Run and installation instructions for copy number calling script
 
Copynumber_parameter_sweep.ipynb & Copynumber_parameter_sweep.html - Validations of the settings used to call copy number in the above main Rscript
 
/References - Contains the Co-ordinate BED file used for calling and sequencing in this publication

/Figures - PDF of the read counts across chromosomes from the parameter sweeps

 

Files

PHJonesGroup/Skrupskelyte_etal_SI_code-1.0.zip

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