Published December 2025 | Version v3

Life Science Competence Centres: Open by Design

Description

Preprint in submission process to Briefings in Bioinformatics

Abstract:

European Life Science Research Infrastructures (LS-RIs), one of the five major RI Science Clusters in Europe, were established to provide access to cutting-edge technologies to the scientific community. Individually, and collectively as the LS-RI cluster, they contribute to the development of the European Open Science Cloud (EOSC), under the aegis of the EOSC Federation. They are actively involved in the design and implementation of Competence Centres (CCs). These aim to increase the accessibility of domain-specific knowledge and tools, enhance interoperability, facilitate sharing and harmonisation of procedures, and promote Open Science and FAIR (Findable, Accessible, Interoperable, Reusable) practices. In this paper, we report a landscape mapping of the existing resources that formed the basis for the construction of CCs. We describe the possible design of CCs and their articulation with the LS-RIs. We focus on community-based ideas and recommendations to increase the potential of CCs to address long-standing challenges in sustainability, governance, scalability, and interoperability of Open Science within EOSC and the European Research Area (ERA) more generally.

This paper provides a description of the nascent LS CCs, built following a survey of needs and services of existing LS-RI communities. When fully implemented, the LS CCs will serve as dynamic hubs to foster innovation, contribute to the EOSC’s future FAIR web of data, and support ongoing developments of the EOSC Federation. They will act as drivers of collaborative and impactful LS research in Europe and beyond. We explore the underlying challenges, and propose solutions, to ensure that the establishment of CCs will add value to the LS RI community, and to the EOSC, in a sustainable way.

Files

PREPRINT_Validated_LS-RIs Cluster CC Paper 21112025_14_38_V7.2.pdf

Files (4.2 MB)

Additional details

Funding

European Commission
OSCARS - O.S.C.A.R.S. - Open Science Clusters' Action for Research and Society 101129751
European Commission
EOSC-Life - Providing an open collaborative space for digital biology in Europe 824087
European Commission
EOSC Beyond - EOSC Beyond: advancing innovation and collaboration for research 101131875
European Commission
EOSC4Cancer - A European-wide foundation to accelerate Data-driven Cancer Research 101058427
European Commission
EOSCpilot - The European Open Science Cloud for Research Pilot Project. 739563
European Commission
EOSC-ENTRUST - EOSC-ENTRUST: A European Network of TRUSTed research environments 101131056
European Commission
OSTrails - Open Science Plan-Track-Assess Pathways 101130187
European Commission
EATRIS-CONNECT - EATRIS-CONNECT 101130349
European Commission
iMagine - Imaging data and services for aquatic science 101058625
European Commission
IMPULSE - IMProving User experience, Long-term sustainability and Services of EU-OPENSCREEN 101132028
European Commission
AI4LIFE - Artificial Intelligence for Image Data Analysis in the Life Sciences 101057970
European Commission
BY-COVID - Beyond COVID 101046203
European Commission
ISIDORe - Integrated Services for Infectious Disease Outbreak Research 101046133
European Commission
EVORA - European Viral Outbreak Response Alliance 101131959
European Commission
DANUBIUS IP - DANUBIUS Implementation Phase Project - DANUBIUS-IP 101079778
European Commission
ENVRI - Common Operations of Environmental Research Infrastructures 283465
European Commission
ENVRI-Hub NEXT - ENVironmental Research Infrastructures delivering an open access Hub and NEXT-level interdisciplinary research framework providing services for advancing science and society 101131141
European Commission
ERIC Forum 2 - Second implementation project for the ERIC Forum 101124559
European Commission
EVERSE - European Virtual Institute for Research Software Excellence 101129744
European Commission
FoundingGIDE - Founding a Global Image Data Ecosystem 101130216
European Commission
IMAGINE - Next generation imaging technologies to probe structure and function of biological specimen across scales in their natural context 101094250
European Commission
MICROBES-4-CLIMATE - Microbial services addressing climate change risks for biodiversity and for agricultural and forestry ecosystems: enabling curiosity-driven research and advancing frontier knowledge 101131818
European Commission
ARISE2 - Career Accelerator for Research Infrastructure Scientists 2nd generation 101178241
European Commission
ELIXIR - European Life-science Infrastructure for Biological Information 211601