COVID-19 mRNA "vaccine" harms: a real-world evidence (RWE) compilation

Compiled by Martin Wucher, MSC Dent Sc (eq DDS), Byram Bridle, PhD, Steven Hatfill, MD, Jessica Rose, PhD, Peter McCullough, MD MPH, Harvey Risch, MD PhD, Kelly Victory, MD, Matt Bain, MD, James Thorp, MD, et al.  

https://zenodo.org/records/17618032

Last updated November 18, 2025. Corresponding author: Steven Hatfill, MD, stevenjhmd@protonmail.com

This compilation originated with the authors’ contributions to TOXIC SHOT: Facing the Dangers of the COVID "Vaccines" (Foreword by Sen. Ron Johnson)

I. Spike protein pathogenicity research library (547/557 peer-reviewed)                                      

Originally part of the outer coat of the SARS-CoV2 virus, where it functions as a “key” to “unlock” (infect) cells, spike proteins are also produced in large amounts by the mRNA “vaccines,” triggering a short-lived immune response in the form of antibodies. However, a growing body of evidence has shown that the spike protein is harmful by itself, including over 500 peer-reviewed scientific papers collected in section I.  A second sub-section (p. 59) organizes the research into 35 subject categories.

II. Spike protein and “vaccine” mRNA biodistribution studies (64/72 peer-reviewed)      

In addition to the pathogenic characteristics of the spike protein antigen, over 60 peer-reviewed studies have demonstrated that both the “vaccine” mRNA encoding for the spike protein antigen and the spike protein itself can leave the injection site to penetrate distant tissues, causing systemic harms.

III. Spike protein and “vaccine” mRNA persistence studies (41/43 peer-reviewed)              

Dozens of peer-reviewed studies confirm that “vaccine” mRNA and the resulting spike protein antigen persist in the tissues of human vaccine recipients and animal test subjects far longer than claimed by public health officials: up to eight weeks in the case of mRNA (Röltgen K et al.) and up to 17 months for spike protein (Ota N et al.).  

IV. Lipid nanoparticle toxicity and allergenicity studies (92/92 peer-reviewed)                        

Over 90 peer-reviewed papers show that ionizable lipid nanoparticles (LNPs) used in the experimental mRNA injections are highly inflammatory on their own, including their polyethylene glycol (PEG) component, an established cause of anaphylaxis (an extreme allergic reaction). Research also suggests much higher anaphylaxis rates following “vaccination” than indicated in official figures.

V. COVID-19 “vaccine” immune imprinting library (148/156 peer-reviewed)                              

Immune imprinting, dubbed “original antigenic sin” by Thomas Francis Jr., occurs when memory B lymphocytes produced in response to an initial viral infection dominate subsequent responses to related viruses. Over 140 peer-reviewed papers suggest that COVID “vaccines” imprinted the immune systems of recipients through exposure to the “wild type” spike protein from the original Wuhan strain, shaping their response to subsequent variants in potentially harmful ways.

VI. SARS-CoV2 vaccine and viral variant research library (83/85 peer-reviewed)                   

In addition to the pathogenicity, distribution, and long persistence of the “vaccine” spike protein, this collection of over 80 peer-reviewed papers suggests that by failing to prevent infection or transmission, the “vaccines” applied strong selective pressure to the fast-mutating SARS-CoV2 virus, quickly giving rise to “vaccine”-resistant variants.

VII. COVID “vaccine” cancer, genotoxicity, and DNA contamination risks (117/122 peer-reviewed)                              

Scientific evidence suggests that the mRNA “vaccines” as well as the adenoviral vector shots (J&J, AstraZeneca) and various inactivated “vaccines” (CoronaVac) can damage DNA and trigger or accelerate the growth of cancers. Research has also revealed contamination of mRNA “vaccines” with residual DNA, a byproduct of the manufacturing process which may be incorporated into cellular DNA during DNA damage repair, permanently altering the human genome.

VIII. APPENDIX. Overview of TOXIC SHOT: Facing the Dangers of the COVID “Vaccines”                                                       

This scientific bombshell shatters official propaganda about the COVID-19 “vaccines,” highlighting their risks for healthy people as well as their failure to stop the pandemic. Chapter after chapter presents damning proof of the myriad harms associated with the “vaccines,” drawing on abundant scientific research to explain why the experimental shots are so dangerous. A call to battle, TOXIC SHOT leaves no doubt that the COVID-19 “vaccines” must be withdrawn from the market immediately.

For readers seeking more information: React19, a global organization advocating for individuals with “vaccine” injuries and their loved ones, has collected over 3,750 published papers documenting “vaccine” injuries available here: https://react19.org/science. The Malone Institute maintains a database of over 770 papers documenting COVID “vaccine” harms available here: https://maloneinstitute.org/reference-project. DailyClout presents a comprehensive analysis of “vaccine” harms drawing on Pfizer’s own clinical trial data in The Pfizer Papers: Pfizer’s Crimes Against Humanity (Skyhorse, 2024).