Published March 15, 2014 | Version v1
Journal article Open

Locul cercetării clinice/epidemiologice în sistemul CDI

Authors/Creators

  • 1. ROR icon Bucharest Emergency University Hospital

Description

Clinical/epidemiologic research (CER) provides the basis of allopathic (mainstream) medicine by supplying the
predictive theories needed for medical practice and health policy making. These theories consist of laws to
probabilistically predict future clinical events based on current and previous measurements. CER studies consist
of observations and experiments performed on patients, toghether with their theoretical interpretation. They
are complemented by pathology, farmacokinetics and signal studies that are also performed in patients, but
explore the relations between measurables rather than clinical events. Purely theoretical studies include meta-
analyses—that are statistical analyses of data pooled from multiple similar studies, and more recently population
pharmacokinetic and pharmacometric studies.
The structure of the CER subsystems in developed countries is similar, and includes medical schools, teaching
(and research) hospitals, epidemic surveillance government institutions, agencies such as the Food and Drug
Administration, and a segment of the industry that organises clinical research for the purpose of testing and
characterisation of drugs, devices and diagnostic and therapeutic machinery.
The performance of the CER subsystem is essential for the proper training of physicians and for the atractivity
of the health system for professional elites.
The CER subsystem, estimated by a variety of metrics, such as the proportion of employees, funds and number
of publications, represents about 6–11% from the overall research system in Romania, compared about 18–31%
in the USA

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Additional titles

Translated title (English)
Clinical/epidemiologic research as part of the R&D system