PROSE (PROfile Standardization Engine): An R package for standardized analysis of time-series profiles.

The R package “PROSE” could be useful in situations where you have time-series data which had been previously analyzed, and thus you have decided in which neighboring time intervals the values are significantly different. In that case, given a vector of significance calls “d” (e.g., from previous analysis) and a vector of “values” (your time-series measurements), the function “prose(d, values)” summarizes the information available in an explicit model. It also provides a vector of means of the values that accounts for the significance contained in “d”, and a vector of standardized values.

Previously the algorithm in PROSE had been used in transcriptomics (RNA-Seq) to obtain "Standardized Expression Profiles" (called "SEP"s; please see the references).