4x4-TETRA Deep Tech Matrix™: A Blueprint for Survival in Science Commercialization

In science, chaos is only an illusion; what appears random is often the result of hidden parameters and missing coordinates. This work introduces 4x4-TETRA Deep Tech Matrix™ (TETRA), a quantum‑inspired framework conceived and developed by Maria Ksenia Witte (Arise Innovations®). Rooted in more than a decade of pattern recognition across laboratories, startups and investment portfolios, TETRA treats a deep tech venture as a state vector in superposition, with evidence, industrialization, market dynamics, governance, regulatory and capital constraints acting as operators on this state. The framework aligns these factors across time and technology‑readiness levels (TRLs), then reverses from an intended exit to derive a probability‑weighted roadmap. This article discloses the conceptual foundation — the what and the why — while keeping the full process protected as intellectual property.