Published November 4, 2025 | Version v1
Computational notebook Open

ecDNA/SV Breakpoint-CRISPR pipeline

  • 1. ROR icon Charité - Universitätsmedizin Berlin
  • 2. Verband Forschender Arzneimittelhersteller eV

Description

This archive contains the prototype workflow (“Breakpoint-CRISPR pipeline”, ec-bkp-PAM) 
used to identify novel PAMs and gRNA candidates at ecDNA and SV breakpoints. 
Provided for reproducibility of analyses in our CancerPAM manuscript. 
Not a packaged software release.

Files

bkp-CRISPR-main.zip

Files (1.8 MB)

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