Welcome to GenProtein Finder!

A Python tool for analyzing protein distribution across multiple genomes, enabling bidirectional searches and comparative genomics analysis.

• Genome-to-Protein Search: Find all proteins present in a specific genome
• Protein-to-Genome Search: Identify which genomes contain a specific protein
• Occurrence Statistics: Analyze protein distribution and identify shared proteins across genomes
• Partial Name Matching: Search genomes using partial names (e.g., "GCA_")
• Interactive Menu: User-friendly command-line interface

• Python 3.6+
• pandas
• openpyxl (for Excel file support)

Install required dependencies:

pip install pandas openpyxl

The script expects an Excel file with the following structure:

• Columns 1-3: Metadata (ignored by the script)
• Columns 4+: Each column represents a genome, containing protein names
• Protein names should be listed in each genome column
• Empty cells are automatically handled

Example:

1. If you are using Linux and running from the terminal, give execution permission to the script:

chmod +x genprotein_finder.py

1. Update the file path in the script:

excel_file = "path/to/your/excel/file.xlsx"

1. Run

python3 genprotein_finder.py

Vinicius Henrique de Oliveira Franzote - vinicius.henrique@unesp.br