SARST2 v2.0.30-nc

Structural similarity search Aided by Ramachandran Sequential Transformation, version 2

About this software

SARST2 (Structural similarity search Aided by Ramachandran Sequential Transformation, version 2) is a high-performance protein structure alignment algorithm for structural similarity searches. It supports both large-scale database searches using a given query protein and pairwise alignments between two structures.

This software is released with the following paper and will be regularly updated through the URLs listed below:

Wei-Cheng Lo*, Arieh Warshel, Chia-Hua Lo, Chia Yee Choke, Yan-Jie Li, Shih-Chung Yen, Jyun-Yi Yang, Shih-Wen Weng (2025, Sep). SARST2 high-throughput and resource-efficient protein structure alignment against massive databases. Nature Communications, https://doi.org/10.1038/s41467-025-63757-9

*Corresponding author (WadeLo@nycu.edu.tw)

Download URLs: https://github.com/NYCU-10lab/sarst https://10lab.ceb.nycu.edu.tw/sarst2

Download

Linux, x86_64 | .tar.gz | .zip

Linux, arm64 | .tar.gz | .zip

macOS, x86_64 | .tar.gz | .zip

macOS, arm64 | .tar.gz | .zip

Windows 10+, x86_64 | .tar.gz | .zip

Windows 10+, arm64 | .tar.gz | .zip

User manual

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