Formulation and Evaluation of Anti-Ageing Cream From Centella Asiatica, Benincasa Hispida and Punica Granatum

ABSTRACT

Skin aging is a natural process influenced by intrinsic and extrinsic factors, leading to wrinkles, dryness, and reduced elasticity. This study aims to formulate and evaluate an anti-aging cream using natural extracts of Centellaasiatica, Benincasahispida, and Punicagranatum, which are rich in flavonoids, tannins, glycosides, and antioxidants. These phytoconstituents possess anti-aging, anti-inflammatory, and emollient properties. A single cream formulation was prepared using juicy and pulpy extracts of the three plants in equal proportions. The cream was evaluated for physical appearance, viscosity, spreadability, and skin irritation. Results showed that the formulation was homogenous, stable, and exhibited good spreadability and permeability. No signs of erythema or edema were observed in the skin irritation test, confirming the formulation's safety and non-toxic nature. The combination of extracts showed enhanced anti-aging effects compared to individual plant extracts, demonstrating synergistic activity. The use of topical delivery for this formulation also ensures better patient compliance and targeted action. In conclusion, the developed herbal anti-aging cream is effective, safe and offers a promising natural approach to managing skin aging.

Keywords: Anti-ageing, Topical formulation, Centellaasiatica, Benincasahispida, Punicagranatum.